Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter20: Acidity And Pka Of Phenols
Section: Chapter Questions
Problem 11E
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Question
![Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate
as it is first formed in the following reaction.
H3C
HCI / H2O
`NH2
reflux
• You do not have to consider stereochemistry.
• Include all valence lone pairs in your answer.
• Do not include counter-ions, e.g., Na", I, in your answer.
• In cases where there is more than one answer, just draw one.
opy
aste
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Transcribed Image Text:Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate
as it is first formed in the following reaction.
H3C
HCI / H2O
`NH2
reflux
• You do not have to consider stereochemistry.
• Include all valence lone pairs in your answer.
• Do not include counter-ions, e.g., Na", I, in your answer.
• In cases where there is more than one answer, just draw one.
opy
aste
Previous
Next
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