An antimicrobial agent shows selective toxicity when specifically: An antimicrobial agent is said to exhibit selective toxicity when it specifically: Select one: O does not induce the development of resistant strains of microorganisms O kills or destroys many species of microorganisms O kills or inhibits the microorganism with minimal or no damage to host cells O penetrates rapidly into host cells and tissues O does not interfere with host defense microorganisms

An antimicrobial agent shows selective toxicity when specifically: An antimicrobial agent is said to exhibit selective toxicity when it specifically: Select one: O does not induce the development of resistant strains of microorganisms O kills or destroys many species of microorganisms O kills or inhibits the microorganism with minimal or no damage to host cells O penetrates rapidly into host cells and tissues O does not interfere with host defense microorganisms

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter12: Body Defenses

Section: Chapter Questions

Problem 1ACR

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Which of the following is true of selective toxicity? O 1) It refers to the process of determining the correct dose of a particular drug O 2) To be effective, an antimicrobial agent must be more toxic to the patient than 2) the pathogen O 3) It contributes to antibiotic resistance O 4) It refers to the body's ability to protect the brain and eye 5) It takes advantage of metabolic and structural differences between host and pathogen
Which of the following would not be a potential side effect of standard antimicrobial drugs? disruption of the host's normal microbiota damage to the host's kidneys allergic reactions in the host inhibition of host protein synthesis
All of the following are true of antibodies EXCEPT: Each individual antibody molecule is specific for more than one type of antigen They are made of proteins They are also called immunoglobulins They are produced in response to antigens They are produced by plasma cells
Which of the following is a criteria used to evaluate an antibiotic? Which of the following is a characteristic or criterion used to evaluate an antibiotic? The answer can be one or more) Select one or more: O a. should not interfere with host defense mechanisms O b. should not kill normal host flora O c. must remain active even in the presence of organic matter O d. show selective toxicity
1) It is sometimes best to use two different antibiotics in order to treat an infection. This might happen because of the : -Symbiotic effects of the drugs -Synergistic effects of the drugs -Antagonistic effects of the two drugs 2) What was the first synthetic antimicrobial? - Salvarsan - Tetracycline - Sulfonimide
list 3 different mechanisms of antibacterial drugs. Example: acting on cell wall, cell membrane, etc
All of the following are methods intracellular pathogens can use to survive inside a host cell EXCEPT create a capsule. Escape the phagosome. survive in the phagolysosome. prevent phagosome-lysosome fusion.
Which of the following is the site of action for penicillin? O Cell wall Cell membrane O Protein O DNA
Below are a list of virulence factors/ strategies paired with an example of an organism that utilizes them. How do each of the following strategies contribute to the virulence of the pathogen? Strategy - Causes the host to produce more receptors (Organism - Rhinovirus) Strategy - Produces gas as a product of fermentation (Organism - Clostridium perfringens) Strategy - Produces a capsule (organism - Klebsiella pneumonia) Strategy - Ability to move between adjacent cells (organism - Cytomegalovirus) Strategy - Ability to use pilus as a motility structure (organism - Pseudomonas aerogenosa)
Many antimicrobials were discovered in the first half of the 20th century. Match the early antimicrobial drugs with their description and/or target disease: salvarsan sulfanilamide penicillin prontosil Choices - first synthetic antimicrobial synthetic dye used to treat streptococcal and staphylococcal infections treatment for syphilis first discovered natural antibiotic
The success of a pathogen in invading an organisms depends on the number and the pathogens. O visibility O adhesiveness adherence O quality of
portal of entry opportunistic Infection morbidity pathogen healthcare-associated infection virulence factors pathogenicity toxemia Entry into the host by a which can cause disease in a healthy host pathogen can be via a which can cause disease in an immunocompromised host which can establish can lead to attachment and avoidance of host defenses, which depend on may be caused by normal biota may be caused by drug- resistant microbes such as enzymes and toxins that may trigger may enhance which together with fever other signs and symptoms define a Reset