Diastereoselectivity O Any/all of these factors O A chiral center with bulky substituents at the alpha-position of the enolate O A chiral center with bulky substituents at the alpha-position of the electrophilic carbonyl O A chiral center with bulky substituents on the amine (and enamine) when using the amine-catalyzed enamine mode or stereoselectivity of the aldol addition step can be inlfuenced by _____?

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter21: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions
Section21.SE: Something Extra
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QUESTION 4
Diastereoselectivity or stereoselectivity of the aldol addition step can be inlfuenced by?
O Any/all of these factors
O A chiral center with bulky substituents at the alpha-position of the enolate
O A chiral center with bulky substituents at the alpha-position of the electrophilic carbonyl
O A chiral center with bulky substituents on the amine (and enamine) when using the amine-catalyzed enamine mode
Transcribed Image Text:QUESTION 4 Diastereoselectivity or stereoselectivity of the aldol addition step can be inlfuenced by? O Any/all of these factors O A chiral center with bulky substituents at the alpha-position of the enolate O A chiral center with bulky substituents at the alpha-position of the electrophilic carbonyl O A chiral center with bulky substituents on the amine (and enamine) when using the amine-catalyzed enamine mode
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