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List and explain in your own words the 5 mechanisms of antimicrobial drug resistance
Introduction:
Antimicrobials selectively destroy/prevent the formation of germs such as bacteria (antibacterial drugs), fungi (antifungal drugs), virus (antiviral drugs), or other parasites (antiparasitic drugs) or reduce their pathogenic action. Antimicrobial drugs include antibiotics, antiseptics, and disinfectants.
Step by step
Solved in 2 steps
- Explain the phenomenon of drug resistance from the standpoint ofmicrobial genetics (include a description of R factors).What properties of drug are relevant for developing modified release drug delivery formulation. Please briefly explain this at your own words.Please give me a discussion/explanation of ( TARGET SELECTION ) part in drug discovery and development.
- Please Write the Drug Discovery Process of Diltiazem? Please write at your own words.What are the different methods for developing modified release drug delivery system ? Discuss about the matrix and encapsulation drug release systems. Please explain at your own words.Biotransformation is an important concept in pharmacology, which amongst others, enables the effective administration of prodrugs. Provide a detailed description of factors influencing the biotransformation of drugs.
- Write two advantages & two disadvantages of using biosimilar drug products insted original innovator drug product.Briefly discuss how we can improve pharmacodynamic properties of H1-Antihistamine drugs?What is the minimal resolution required for gleaning insights into structures of drug-drug target complex? 100A 2.5A 5A 10A 0.5A
- Please give me a discussion which include all aspects in drug discovery and development, from preclinical studies until clinical study.- Lead discovery- Target selection- Medicinal chemistry- In vitro studies- In vivo studies- Clinical studiesName and describe three mechanisms of acquired antimicrobial resistance tools that microbes may use to thwart drug action.Choose the false statement below: O Using three different classes of antimicrobials in combination greatly decreases the chance of developing resistance because the drug resistance strategy for one is the same for others. O Drug resistance to antimicrobials has proven to be extensive against chemotherapeutics as well as other chemical antimicrobials. O Collateral damage is a term that refers to the killing of normal body flora as well as pathogenic bacteria when taking antimicrobials or antibiotics.