sickle cell anemia is due to a recessive allele. in a population of 1000 individuals 35 have sickle cell anemia approximately how many carriers are present in this population
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- Sickle cell anemia is a genetically inherited autosomal recessive trait in which results in a condition that there are not enough healthy red blood cells to carry oxygen throughout the body due to the production of red blood cells that are sickle shaped. The frequency of the sickle cell condition is as high as 10% in Central Africa compared to 0.5% in the United States. Calculate the frequency of the normal and carries of the sickle cell condition.The allele for sickle anemia is found at higher frequencies in central Africa than in other parts of the world. What are the advantage and disadvantages?Sickle cell anemia is an inheritable red blood cell disorder that results in sickle-shaped red blood cells. The sickle-shaped red blood cells can stick to blood vessel walls and cause a blockage or slow the movement of blood throughout the body. Individuals who are heterozygous produce both normal and sickle-shaped red blood cells which gives them resistance to malaria but they do not develop sickle cell anemia (so heterozygotes are unaffected on the pedigree).Let HbS be the allele for sickle cell anemia and let HbA be the allele for normal red blood cells. Which of the following rows provides the correct genotypes for individuals I-2, I-4, II-1, and III-1? Select one: a. I-2 I-4 II-1 III-1 HbA_ HbAHbS HbAHbS HbA_ b. I-2 I-4 II-1 III-1 HbA_ HbAHbS HbAHbS HbAHbS c. I-2 I-4 II-1 III-1 HbAHbS HbAHbS HbAHbS HbAHbS d. I-2 I-4 II-1 III-1 HbAHbA HbAHbA HbAHbA HbAHbA
- Sickle cell disease (SCD) affects millions of people throughout the world; the CDC "Centers for Disease Control and Prevention" estimated that in the United States: SCD affects approximately 100,000 Americans. SCD occurs among about 1 out of every 365 Black or African-American births. SCD occurs among about 1 out of every 16,300 Hispanic-American births. About 1 in 13 Black or African-American babies is born with sickle cell trait (SCT). What do sickle cells mean? And how does this disease affect the human body? Why do Some experts state it can have some benefits?Sickle cell anemia is a disease that is caused by a mutation in the gene that produces hemoglobin. Hemoglobin carries oxygen in red blood cells. The HbA allele produces normal hemoglobin and the HbS allele produces hemoglobin that sticks together and causes red blood cells to sickle. Heterozygous individuals (HbAHbS) produce both normal and "sickle" hemoglobin so the HbA and HbS alleles are codominant. Heterozygotes do not develop sickle cell anemia and are described as having the sickle cell trait. Individuals that are homozygous for the sickle allele (HbSHbS) only produce "sickle" hemoglobin and develop sickle cell disease. A man with the sickle cell trait married a woman with the sickle cell trait. Determine the probability that they will have children with the sickle cell trait or sickle cell disease.Record your answer as a value between 0 and 1 rounded to two decimal places. AnswerAnother couple is concerned their child will be born with sickle cell anemia. The woman does not have sickle cell anemia. The woman’s mother had sickle cell anemia and her father was a carrier of the sickle cell gene. The man knows that he is not a carrier of the sickle cell gene. What is the probability that the child will be a carrier of sickle cell anemia? please include a punnett square
- A man with hemophilia has a daughter of normal phenotype. She marries a man who is normal for the trait. The probability of their son to be a hemophiliac is 1/4. Its true or false? Explain.A graduating nursing student wanted to know the different blood groups and how they can be inherited. She understood that multiple allele is the inheritance pattern for ABO blood type while complete dominance for Rh factor (Rh + is dominant over Rh -). Now she wanted to know what the probable blood types from the 3 systems on her future children are. Consider the nursing student has AB, Rh negative and her current husband has O, heterozygous Rh positive. 1. What is the probability of having a child with a blood type of type O? A. 25% B. 100% C. 75% D. 50% E. 0% 2. What is the probability of having a child with a blood type of type A Rh positive? A. 1/4 B. 3/8 C. 1/2 D. 3/4 E. 1/8 3. What is the probability of having a child with a blood type of type B Rh negative? A. 3/4 B. 1/8 C. 1/4 D. 1/2 E. 3/8 4. heterozygous Rh positive. What are the possible blood types of her children? A. A Rh+, A Rh-, B Rh+, B Rh-, O Rh+, O Rh- B. A Rh+, B…A couple are both phenotypically normal but their son suffers from hemophilla, a sex linked recessive disorder. What fraction of their children are likely to suffer from hemophilia. what fraction are likely to be carriers.
- A group of people are studiedd with made up blood types AZ blood group which is a blood type controlled by a single gene with two loci. Indivuals in this group may be “D” ( = that their homozygous for the “D” allele) “Z” = homozygous for the “z” allele. *DZ= Heterzygous ** Total Number of people with each type 102 people have D type blood 96 have blood type DZ 31 people in this group have type “Z” QUESTION Now please calculate the allele frequencies of “D”and “Z” In doing so use variable “P”= to represent “D” allele And “q”= to represent “Z” allele Calculate the genotype frequencies expected in the population based of the q and p frequencies you calculate. A)frequency of the “Z” allele in the population ________ B)Frequency of the “D” allele in the populations__________ C)A number of expected individuals with the “DD” genotype in the population? __________ D) NUMBER OF EXPECTED INDIVIDUALS WITH THE “ZZ” GENOTYPE IN THE POPULATION?_______ E) A NUMBER OF EXPECTED…What would happen to the frequency of heterozygous carriers of sickle-cell anemia (with AS genotype) if mosquitoes were completely wiped out in a large region?A man who has type O blood has a child with a woman who has type A blood. The woman's mother has type AB blood and her father, type B. What is the probability that the child has type A blood? O 0% O 75% O 100% 50% O 25%
