The first step of the lysozyme reaction (catalytic mechanism) is shown in the figure below. Which statement regarding lysozyme is true? Glu 35 HO O(NAM) to (NAG) Asp 52 www a. The local environment of Asp 52 significantly changes its pka. Ob. Glu 35 has an unusually low pKa due to its hydrophobic environment. Oc. Glu 35 provides acid/base assistance during catalysis. Od. Glu 35 acts as a nucleophile during catalysis.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
Question
The first step of the lysozyme reaction (catalytic mechanism) is shown in the figure below. Which statement regarding lysozyme is true?
Glu 35
HO
O(NAM)
R
(NAG)
Asp 52
a. The local environment of Asp 52 significantly changes its pka.
b. Glu 35 has an unusually low pKa due to its hydrophobic environment.
c. Glu 35 provides acid/base assistance during catalysis.
d. Glu 35 acts as a nucleophile during catalysis.
Transcribed Image Text:The first step of the lysozyme reaction (catalytic mechanism) is shown in the figure below. Which statement regarding lysozyme is true? Glu 35 HO O(NAM) R (NAG) Asp 52 a. The local environment of Asp 52 significantly changes its pka. b. Glu 35 has an unusually low pKa due to its hydrophobic environment. c. Glu 35 provides acid/base assistance during catalysis. d. Glu 35 acts as a nucleophile during catalysis.
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 4 steps

Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON