The mucosal immune system provides protection for a vast area of the body and contains three-quarters of all the lymphocytes in the body. A key feature of the mucosal immune system is its Inability to provide adequate protection, leading to millions of deaths per year due to mucosal infections Use of the identical mechanisms and response features compared to the systemic immune system Ability to respond to thousands of different bacterial species Ability to avoid responding to the large numbers and differing species of commensal microbes In addition to Peyer's patches that resemble systemic lymph nodes, the intestinal epithelium also contains several thousand isclated lymphoid follicles. Unlike the organized secondary lymphoid tissues in the mucosal immune system, these lymphoid foilicles: O Contain mostiy T cells and very few B cells O Are not connected to the lymphatic system that drains to lymph nodes Develop only after birth in response to colonization by commensal microbes O Have no M cells to deliver gut antigens to the lymphocytes in the follicles

The mucosal immune system provides protection for a vast area of the body and contains three-quarters of all the lymphocytes in the body. A key feature of the mucosal immune system is its Inability to provide adequate protection, leading to millions of deaths per year due to mucosal infections Use of the identical mechanisms and response features compared to the systemic immune system Ability to respond to thousands of different bacterial species Ability to avoid responding to the large numbers and differing species of commensal microbes In addition to Peyer's patches that resemble systemic lymph nodes, the intestinal epithelium also contains several thousand isclated lymphoid follicles. Unlike the organized secondary lymphoid tissues in the mucosal immune system, these lymphoid foilicles: O Contain mostiy T cells and very few B cells O Are not connected to the lymphatic system that drains to lymph nodes Develop only after birth in response to colonization by commensal microbes O Have no M cells to deliver gut antigens to the lymphocytes in the follicles

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter12: Body Defenses

Section: Chapter Questions

Problem 14RE

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