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When blood is taken out of the body for processing into an extracorporeal device, a major concern is that the level of shear stress to which the blood is exposed should be less than a critical level (roughly 1000 dyne/cm²). Exposure to shear stress levels higher than this can lead to lysis of the red blood cells, activation of platelets, and initiation of the clotting cascade. Consider the flow of blood through a device that has a set of parallel tubes each with a diameter of 1 mm and a length of 10 cm. What is the maximum pressure drop that should be used for such a device if the highest shear levels in the device occur in these tubes? Blood has a viscosity of 0.0445 g/cm's.

When blood is taken out of the body for processing into an extracorporeal device, a major concern is that the level of shear stress to which the blood is exposed should be less than a critical level (roughly 1000 dyne/cm²). Exposure to shear stress levels higher than this can lead to lysis of the red blood cells, activation of platelets, and initiation of the clotting cascade. Consider the flow of blood through a device that has a set of parallel tubes each with a diameter of 1 mm and a length of 10 cm. What is the maximum pressure drop that should be used for such a device if the highest shear levels in the device occur in these tubes? Blood has a viscosity of 0.0445 g/cm's.

Introduction to Chemical Engineering Thermodynamics
Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
Section: Chapter Questions
Problem 1.1P
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When blood is taken out of the body for processing into an extracorporeal device, a major concern is that the level of shear stress to which the blood is exposed should be less than a critical level (roughly 1000 dyne/cm²). Exposure to shear stress levels higher than this can lead to lysis of the red blood cells, activation of platelets, and initiation of the clotting cascade. Consider the flow of blood through a device that has a set of parallel tubes each with a diameter of 1 mm and a length of 10 cm. What is the maximum pressure drop that should be used for such a device if the highest shear levels in the device occur in these tubes? Blood has a viscosity of 0.0445 g/cm's.
Transcribed Image Text:When blood is taken out of the body for processing into an extracorporeal device, a major concern is that the level of shear stress to which the blood is exposed should be less than a critical level (roughly 1000 dyne/cm²). Exposure to shear stress levels higher than this can lead to lysis of the red blood cells, activation of platelets, and initiation of the clotting cascade. Consider the flow of blood through a device that has a set of parallel tubes each with a diameter of 1 mm and a length of 10 cm. What is the maximum pressure drop that should be used for such a device if the highest shear levels in the device occur in these tubes? Blood has a viscosity of 0.0445 g/cm's.
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