A hiker on Mount Everest exhausts their food. In these low oxygen conditions, with no food, the hiker runs out of glucose and ketone bodies important for energy production in neurons, and hence produces lower levels of ATP. 1. Of the following proteins, which protein's function is most directly/likely to be affected and why? (Ligand-gated Na' / K' channels, Ligand-gates CT channels, Na' /K", Voltage-gated Na channels, Ligand-gated K' channels) 2. Would the resting membrane potential be closer to or further away from the threshold voltage? Or, would there be no change in resting membrane potential? Please briefly explain your answer. 3. Compared to normal conditions, is this hiker more likely, less likely, or is there no change in likelihood to generate an action potential in response to the same excitatory input? 4. How would the action potential change? Below, we have a diagram of a normal action potential. Please draw any qualitative differences in the action potential (and the resting membrane potential), and explain your answer. 5. The hiker finds candy bars at a base camp and replenishes their glucose stores. ATP is now produced at normal levels again, and any previous changes to the action potential are fully reversed (the action potential is completely normal again). However, the candy bars contained a toxin called Blacker toxin, which causes voltage-gated Na+ channels to inactivate more slowly. How would the action potential change? Below we have a diagram of a normal action potential. Please draw any qualitative differences in the action potential (and the resting membrane potential) and explain your answer.
A hiker on Mount Everest exhausts their food. In these low oxygen conditions, with no food, the hiker runs out of glucose and ketone bodies important for energy production in neurons, and hence produces lower levels of ATP. 1. Of the following proteins, which protein's function is most directly/likely to be affected and why? (Ligand-gated Na' / K' channels, Ligand-gates CT channels, Na' /K", Voltage-gated Na channels, Ligand-gated K' channels) 2. Would the resting membrane potential be closer to or further away from the threshold voltage? Or, would there be no change in resting membrane potential? Please briefly explain your answer. 3. Compared to normal conditions, is this hiker more likely, less likely, or is there no change in likelihood to generate an action potential in response to the same excitatory input? 4. How would the action potential change? Below, we have a diagram of a normal action potential. Please draw any qualitative differences in the action potential (and the resting membrane potential), and explain your answer. 5. The hiker finds candy bars at a base camp and replenishes their glucose stores. ATP is now produced at normal levels again, and any previous changes to the action potential are fully reversed (the action potential is completely normal again). However, the candy bars contained a toxin called Blacker toxin, which causes voltage-gated Na+ channels to inactivate more slowly. How would the action potential change? Below we have a diagram of a normal action potential. Please draw any qualitative differences in the action potential (and the resting membrane potential) and explain your answer.
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter4: Principles Of Neural And Hormonal Communication
Section: Chapter Questions
Problem 5RE: Second-messenger systems ultimately bring about the desired cell response by inducing a change in...
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help me with part 4 and 5 please
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