Which of the following statements is false concerning the ‘tight binding site’ of ATP Synthase within the natural environment of the mitochondria? Group of answer choices ATP is released from the tight binding site This is a binding site found within an αβ subunits of the F1 portion of ATP Synthase The tight binding forces the reaction of ADP + Pi → ATP The tight binding site has the lowest KM for ATP

Which of the following statements is false concerning the ‘tight binding site’ of ATP Synthase within the natural environment of the mitochondria? Group of answer choices ATP is released from the tight binding site This is a binding site found within an αβ subunits of the F1 portion of ATP Synthase The tight binding forces the reaction of ADP + Pi → ATP The tight binding site has the lowest KM for ATP

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter2: Cell Physiology

Section: Chapter Questions

Problem 10RE: Using the answer code on the right, indicate which form of energy production is being described: 1....

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Which of the following statements best explains why the activity of ATP-citrate lyase and malic enzyme are often paired together? The use of ATP by ATP-citrate lyase means that NADH needs to be regenerated cytosolically so that more ATP can be generated via shuttle systems and replace the ATP used by ATP-citrate lyase ATP-citrate lyase produces ATP and malic enzyme produces NADPH, both needed in the fatty acid biosynthetic pathway The activity of ATP-citrate lyase and malic enzyme never are correlated, they always function in different realms of metabolism The generation of acetyl CoA is a substrate for fatty acid synthesis in the cytosol and NADPH is generated as the anabolic electron carrier
Which is the correct link between conformation of the beta-subunit of the F1 component of the ATP synthase and ADP+P¡ or ATP? loose Binding Change Mechanism binding ATP ADP+P ATP Crepeat ADP ADP +P; ATP ATP +P; tight binding open ATP loose => binding ADP+Pi open => catalyzes ADP+P¡ into ATP tight => releases ATP open => releases ADP+P¡
Describe the conformational changes (including substrates that bind to the different conformations) that occur in the F1 domain of ATP Synthase that result from protons flowing through the Fo domain down their concentration gradient:
A poison that prevents the transfer of electrons from the last [Fe-S] cluster of Complex I to coenzyme Q is added to a suspension of actively respiring mitochondria. Which of the following will be observed? ATP production would be impaired due to the uncoupling of oxidative phosphorylation from electron transport. ATP production would be reduced due to inhibition of the CoQ subunit of ATP synthase. ATP production would be reduced due to a decrease in the number of protons pumped out of the mitochondrial matrix. ATP production would be halted completely due to the block in electron transport through the electron transport chain.
Which of the following regarding the ATP Synthase is INCORRECT? Protons flow through the a and c subunits The translocation of four protons through the ATP synthase fuels the synthesis of one ATP molecule The F1 domain can function as an ATPase The y subunit rotates while the xß dimers are stationary
The AG of the reaction C6H12O6 + 60₂ --> 6CO₂ + 6H₂O is -686 kcal/mol glucose oxidized. The AG of the reaction ADP + P₁ --> ATP + H₂O is + 7.3 kcal/mol ATP synthesized. The oxidation of glucose can be coupled to the synthesis of ATP. If the coupling is 50% efficient, how many molecules of ATP can be synthesized per molecule of glucose oxidized? Round your answer to the nearest whole number.
b) Place a 'Yes' or a 'No' in the appropriate boxes that correspond to each listed feature of cellular respiration. You may need to state 'Yes' or 'No' in more than one box in a particular row in some cases. Cellular Respiration Feature Involved in aerobic respiration Occurs in the mitochondrial matrix Pyruvate molecules are produced Acetyl COA combines with a 4 carbon molecule Electrons are passed between protein carriers ATP is produced NAD+ gains hydrogen FADH₂ loses hydrogen Glycolysis Yes / No Krebs Cycle Yes / No Electron Transport chain Yes / No
b) Place a 'Yes' or a 'No' in the appropriate boxes that correspond to each listed feature of cellular respiration. You may need to state 'Yes' or 'No' in more than one box in a particular row in some cases. Cellular Respiration Feature Involved in aerobic respiration Occurs in the mitochondrial matrix Pyruvate molecules are produced Acetyl CoA combines with a 4 carbon molecule Electrons are passed between protein carriers ATP is produced NAD* gains hydrogen FADH₂ loses hydrogen Glycolysis Yes / No Krebs Cycle Yes / No Electron Transport chain Yes/No 90+
Oxidative phosphorylation generates ATP using the reducing power of [NADH, FADH2 or malate] to move electrons down a series of carriers to ultimately produce a [phosphate gradient or protons gradient] across the inner mitochondrial membrane, which is used by ATP synthase to make ATP. ATP synthase harnesses the energy stored in both [charge and concentration gradients or electostatic and van der waals interations] to achieve high energy phosphate bond synthesis. If the ion gradient across the inner membrane is dissipated by the expression of UCP1, ATP is not synthesized and [heat is generated or electron transport is blocked]. The final electron acceptor in the electron transport chain is [oxygen or carbon dioxide] with water as a product.
Where is ATP produced by oxidative phosphorylation? (where is it located immediately after the moment of synthesis) Group of answer choices the mitochondrial matrix the cytoplasm the intermembrane space the inner mitochondrial membrane Which of the following most readily donates electrons? (strongest reducing agent) Group of answer choices NADH NAD+ Ubiquinone lactate Protons first enter ATP synthase through which subunit? Group of answer choices β c γ a
The AG of the reaction C6H1206+602 --> 6 CO2 + 6H₂O is -686 kcal/mol glucose oxidized. The AG of the reaction ADP + P --> ATP + H₂O is + 7.3 kcal/mol ATP synthesized. The oxidation of glucose can be coupled to the synthesis of ATP. If the coupling is 50% efficient, how many molecules of ATP can be synthesized per molecule of glucose oxidized? Round your answer to the nearest whole number. Type your answer... rces K esc Q 7 c с 72 W #3 E 14 R LL Search or type URL % 65 T G A MacBook Pro 6 Y H & 7 U * 8 + - ( 9 J ၂ ။ K 0 ) 0 L P { + 11 } ] Submit delete return
Which of the following statements about the Krebs Cycle is true? There may be more than one answer. Select any and all that apply. It is a linear 10 step pathway It generates ATP molecules directly through oxidative phosphorylation It produces two molecules of carbon dioxide It begins with acetyl coenzyme A and oxaloacetate combining It converts glucose to carbon dioxide It is a point of entry for the products of amino acid catabolism to be converted into energy It is an anaerobic process that produces molecules for an aerobic process that comes later The first step is the breakdown of glucose into glyceraldehyde-3-phosphate